What does the term "inversion" signify in genetics?

The term "inversion" in genetics refers specifically to a segment of DNA that is reversed end to end. This means that a piece of chromosome has broken off, flipped around 180 degrees, and then reattached. This structural change can affect gene expression and the function of genes located within the inverted segment or adjacent to it. Inversions can impact the way cells interpret genetic information and can sometimes lead to genetic disorders or contribute to the evolution of species as they might affect how traits are inherited. Understanding this concept is crucial in the study of genetics, especially regarding chromosome structure and function.